A Polyuridine Insertion in the 3′ Untranslated Region of Classical Swine Fever Virus Activates Immunity and Reduces Viral Virulence in Piglets

Low-virulence classical swine fever virus (CSFV) strains make CSF eradication particularly difficult. Few data are available on the molecular determinants of CSFV virulence. The aim of the present study was to assess a possible role for CSFV virulence of a unique, uninterrupted 36-uridine (poly-U) s...

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Detalles Bibliográficos
Autores principales: Wang, Miaomiao, Liniger, Matthias, Muñoz-González, Sara, Bohórquez, José Alejandro, Hinojosa, Yoandry, Gerber, Markus, López-Soria, Sergio, Rosell, Rosa, Ruggli, Nicolas, Ganges, Llilianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955259/
https://www.ncbi.nlm.nih.gov/pubmed/31645448
http://dx.doi.org/10.1128/JVI.01214-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955259/
https://www.ncbi.nlm.nih.gov/pubmed/31645448
http://dx.doi.org/10.1128/JVI.01214-19

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