Cargando…

Three Amino Acid Changes in Avian Coronavirus Spike Protein Allow Binding to Kidney Tissue

Infectious bronchitis virus (IBV) infects ciliated epithelial cells in the chicken respiratory tract. While some IBV strains replicate locally, others can disseminate to various organs, including the kidney. Here, we elucidate the determinants for kidney tropism by studying interactions between the...

Descripción completa

Detalles Bibliográficos
Autores principales: Bouwman, Kim M., Parsons, Lisa M., Berends, Alinda J., de Vries, Robert P., Cipollo, John F., Verheije, Monique H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955270/
https://www.ncbi.nlm.nih.gov/pubmed/31694947
http://dx.doi.org/10.1128/JVI.01363-19