An inhibitor of complement C5 provides structural insights into activation

The complement system is a crucial part of innate immune defenses against invading pathogens. The blood-meal of the tick Rhipicephalus pulchellus lasts for days, and the tick must therefore rely on inhibitors to counter complement activation. We have identified a class of inhibitors from tick saliva...

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Detalles Bibliográficos
Autores principales: Reichhardt, Martin P., Johnson, Steven, Tang, Terence, Morgan, Thomas, Tebeka, Nchimunya, Popitsch, Niko, Deme, Justin C., Jore, Matthijs M., Lea, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955305/
https://www.ncbi.nlm.nih.gov/pubmed/31871188
http://dx.doi.org/10.1073/pnas.1909973116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955305/
https://www.ncbi.nlm.nih.gov/pubmed/31871188
http://dx.doi.org/10.1073/pnas.1909973116

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