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An inhibitor of complement C5 provides structural insights into activation

The complement system is a crucial part of innate immune defenses against invading pathogens. The blood-meal of the tick Rhipicephalus pulchellus lasts for days, and the tick must therefore rely on inhibitors to counter complement activation. We have identified a class of inhibitors from tick saliva...

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Detalles Bibliográficos
Autores principales:	Reichhardt, Martin P., Johnson, Steven, Tang, Terence, Morgan, Thomas, Tebeka, Nchimunya, Popitsch, Niko, Deme, Justin C., Jore, Matthijs M., Lea, Susan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955305/ https://www.ncbi.nlm.nih.gov/pubmed/31871188 http://dx.doi.org/10.1073/pnas.1909973116

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