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Retroviruses drive the rapid evolution of mammalian APOBEC3 genes

APOBEC3 (A3) genes are members of the AID/APOBEC gene family that are found exclusively in mammals. A3 genes encode antiviral proteins that restrict the replication of retroviruses by inducing G-to-A mutations in their genomes and have undergone extensive amplification and diversification during mam...

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Detalles Bibliográficos
Autores principales: Ito, Jumpei, Gifford, Robert J., Sato, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955324/
https://www.ncbi.nlm.nih.gov/pubmed/31843890
http://dx.doi.org/10.1073/pnas.1914183116