A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes

Small cell carcinoma of the bladder (SCCB) is a rare and lethal phenotype of bladder cancer. The pathogenesis and molecular features are unknown. Here, we established a genetically engineered SCCB model and a cohort of patient SCCB and urothelial carcinoma samples to characterize molecular similarit...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Smith, Bryan A., Balanis, Nikolas G., Tsai, Brandon L., Nguyen, Kim, Cheng, Michael W., Obusan, Matthew B., Esedebe, Favour N., Patel, Saahil J., Zhang, Hanwei, Clark, Peter M., Sisk, Anthony E., Said, Jonathan W., Huang, Jiaoti, Graeber, Thomas G., Witte, Owen N., Chin, Arnold I., Park, Jung Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955337/
https://www.ncbi.nlm.nih.gov/pubmed/31871155
http://dx.doi.org/10.1073/pnas.1915770117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955337/
https://www.ncbi.nlm.nih.gov/pubmed/31871155
http://dx.doi.org/10.1073/pnas.1915770117

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