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Molecular mechanism of leukocidin GH–integrin CD11b/CD18 recognition and species specificity

Host–pathogen interactions are central to understanding microbial pathogenesis. The staphylococcal pore-forming cytotoxins hijack important immune molecules but little is known about the underlying molecular mechanisms of cytotoxin–receptor interaction and host specificity. Here we report the struct...

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Detalles Bibliográficos
Autores principales: Trstenjak, Nikolina, Milić, Dalibor, Graewert, Melissa A., Rouha, Harald, Svergun, Dmitri, Djinović-Carugo, Kristina, Nagy, Eszter, Badarau, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955338/
https://www.ncbi.nlm.nih.gov/pubmed/31852826
http://dx.doi.org/10.1073/pnas.1913690116