Shear force sensing of epithelial Na(+) channel (ENaC) relies on N-glycosylated asparagines in the palm and knuckle domains of αENaC

Mechanosensitive ion channels are crucial for normal cell function and facilitate physiological function, such as blood pressure regulation. So far little is known about the molecular mechanisms of how channels sense mechanical force. Canonical vertebrate epithelial Na(+) channel (ENaC) formed by α-...

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Detalles Bibliográficos
Autores principales: Knoepp, Fenja, Ashley, Zoe, Barth, Daniel, Baldin, Jan-Peter, Jennings, Michael, Kazantseva, Marina, Saw, Eng Leng, Katare, Rajesh, Alvarez de la Rosa, Diego, Weissmann, Norbert, Fronius, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955349/
https://www.ncbi.nlm.nih.gov/pubmed/31871197
http://dx.doi.org/10.1073/pnas.1911243117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955349/
https://www.ncbi.nlm.nih.gov/pubmed/31871197
http://dx.doi.org/10.1073/pnas.1911243117

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