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A novel direct method to determine adherence to atorvastatin therapy in patients with coronary heart disease

AIMS: Objective methods to monitor statin adherence are needed. We have established a liquid chromatography–tandem mass spectrometry assay for quantification of atorvastatin and its metabolites in blood. This study aimed to develop an objective drug exposure variable with cut‐off values to discrimin...

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Detalles Bibliográficos
Autores principales: Kristiansen, Oscar, Vethe, Nils T., Fagerland, Morten W., Bergan, Stein, Munkhaugen, John, Husebye, Einar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955401/
https://www.ncbi.nlm.nih.gov/pubmed/31495943
http://dx.doi.org/10.1111/bcp.14122