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Polyethylene glycol loxenatide (PEX168) in subjects with renal impairment: A pharmacokinetic study

AIMS: Type 2 diabetes mellitus (T2DM) is commonly complicated by renal impairment. Polyethylene glycol loxenatide (PEX168) is a novel long‐acting glucagon‐like peptide‐1 receptor agonist for T2DM. PEX168 pharmacokinetics was studied to identify requirements for dose‐modification in T2DM complicated...

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Detalles Bibliográficos
Autores principales: Wang, Jianwen, Huang, Jie, Li, Wei, Tang, Shiqi, Sun, Jian, Zhang, Xianming, Liu, Jun, Yi, Bin, Liu, Jishi, Zhang, Xingfei, Yang, Qian, Yang, Xiaoyan, Yang, Shuang, Yang, Guoping, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955414/
https://www.ncbi.nlm.nih.gov/pubmed/31396983
http://dx.doi.org/10.1111/bcp.14091