Population pharmacokinetic modelling and simulation of fremanezumab in healthy subjects and patients with migraine

AIMS: Fremanezumab is a fully humanized IgG(2)Δa/κ monoclonal antibody specific for calcitonin gene‐related peptide developed and approved for the preventive treatment of migraine in adults. The population pharmacokinetics (PK) of fremanezumab were characterized in healthy subjects and patients with...

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Detalles Bibliográficos
Autores principales: Fiedler‐Kelly, Jill B., Cohen‐Barak, Orit, Morris, Denise N., Ludwig, Elizabeth, Rasamoelisolo, Michele, Shen, Honglue, Levi, Micha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955415/
https://www.ncbi.nlm.nih.gov/pubmed/31418911
http://dx.doi.org/10.1111/bcp.14096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955415/
https://www.ncbi.nlm.nih.gov/pubmed/31418911
http://dx.doi.org/10.1111/bcp.14096

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