A pH-Responsive Charge-Reversal Drug Delivery System with Tumor-Specific Drug Release and ROS Generation for Cancer Therapy

INTRODUCTION: Poor cell uptake and incomplete intracellular drug release are the two major challenges for polymeric prodrug-based drug delivery systems (PPDDSs) in cancer treatment. METHODS: Herein, a PPDDS with pH-induced surface charge-reversal and reactive oxygen species (ROS) amplification for R...

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Detalles Bibliográficos
Autores principales: Xu, Chen, Song, Rijin, Lu, Pei, Chen, Jianchun, Zhou, Yongqiang, Shen, Gang, Jiang, Minjun, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955620/
https://www.ncbi.nlm.nih.gov/pubmed/32021165
http://dx.doi.org/10.2147/IJN.S230237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955620/
https://www.ncbi.nlm.nih.gov/pubmed/32021165
http://dx.doi.org/10.2147/IJN.S230237

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