Development of a Novel Quinoline Derivative as a P-Glycoprotein Inhibitor to Reverse Multidrug Resistance in Cancer Cells

Multidrug resistance (MDR) is one of conventional cancer chemotherapy’s limitations. Our group previously synthesized a series of quinoline-based compounds in an attempt to identify novel anticancer agents. With a molecular docking analysis, the novel compound 160a was predicted to target p-glycopro...

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Detalles Bibliográficos
Autores principales: Zhou, Yuanyuan, Chung, Po-yee, Ma, Jessica Yuen-wuen, Lam, Alfred King-yin, Law, Simon, Chan, Kwok-wah, Chan, Albert Sun-chi, Li, Xingshu, Lam, Kim-hung, Chui, Chung-hin, Tang, Johnny Cheuk-on
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955663/
https://www.ncbi.nlm.nih.gov/pubmed/31581572
http://dx.doi.org/10.3390/biology8040075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955663/
https://www.ncbi.nlm.nih.gov/pubmed/31581572
http://dx.doi.org/10.3390/biology8040075

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