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Reduced Apoptotic Injury by Phenothiazine in Ischemic Stroke through the NOX-Akt/PKC Pathway

Phenothiazine treatment has been shown to reduce post-stroke ischemic injury, though the underlying mechanism remains unclear. This study sought to confirm the neuroprotective effects of phenothiazines and to explore the role of the NOX (nicotinamide adenine dinucleotide phosphate oxidase)/Akt/PKC (...

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Detalles Bibliográficos
Autores principales: Tong, Yanna, Elkin, Kenneth B., Peng, Changya, Shen, Jiamei, Li, Fengwu, Guan, Longfei, Ji, Yu, Wei, Wenjing, Geng, Xiaokun, Ding, Yuchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955743/
https://www.ncbi.nlm.nih.gov/pubmed/31847503
http://dx.doi.org/10.3390/brainsci9120378