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Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats

BACKGROUND: Hemorrhagic shock induces the cognitive deficiency. Sevoflurane postconditioning has been documented to provide neuroprotection against ischemic–reperfusion injury by suppressing apoptosis. Mitochondrial permeability transition pore (mPTP) plays an important role in apoptosis, but it is...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Huang, Li, Wang, Jingxian, Zhang, Muchun, Zhang, Ye, Hu, Xianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955830/
https://www.ncbi.nlm.nih.gov/pubmed/31833229
http://dx.doi.org/10.1002/brb3.1501