Sugar and Polymer Excipients Enhance Uptake and Splice-Switching Activity of Peptide-Dendrimer/Lipid/Oligonucleotide Formulations

Non-viral transfection vectors are commonly used for oligonucleotide (ON) delivery but face many challenges before reaching the desired compartments inside cells. With the support of additional compounds, it might be more feasible for a vector to endure the barriers and achieve efficient delivery. I...

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Detalles Bibliográficos
Autores principales: Saher, Osama, Lehto, Taavi, Gissberg, Olof, Gupta, Dhanu, Gustafsson, Oskar, Andaloussi, Samir EL, Darbre, Tamis, Lundin, Karin E., Smith, C. I. Edvard, Zain, Rula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955847/
https://www.ncbi.nlm.nih.gov/pubmed/31835435
http://dx.doi.org/10.3390/pharmaceutics11120666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955847/
https://www.ncbi.nlm.nih.gov/pubmed/31835435
http://dx.doi.org/10.3390/pharmaceutics11120666

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