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Histone Deacetylases and Their Inhibitors in Cancer Epigenetics

Histone deacetylases (HDAC) and histone deacetylase inhibitors (HDACi) have greatly impacted the war on cancer. Their role in epigenetics has significantly altered the development of anticancer drugs used to treat the most rare, persistent forms of cancer. During transcription, HDAC and HDACi are us...

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Detalles Bibliográficos
Autor principal: Hassell, Kelly N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955926/
https://www.ncbi.nlm.nih.gov/pubmed/31683808
http://dx.doi.org/10.3390/diseases7040057