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A Non-Viral Plasmid DNA Delivery System Consisting on a Lysine-Derived Cationic Lipid Mixed with a Fusogenic Lipid

The insertion of biocompatible amino acid moieties in non-viral gene nanocarriers is an attractive approach that has been recently gaining interest. In this work, a cationic lipid, consisting of a lysine-derived moiety linked to a C(12) chain (LYCl) was combined with a common fusogenic helper lipid...

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Detalles Bibliográficos
Autores principales: Martínez-Negro, María, Sánchez-Arribas, Natalia, Guerrero-Martínez, Andrés, Moyá, María Luisa, Tros de Ilarduya, Conchita, Mendicuti, Francisco, Aicart, Emilio, Junquera, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956073/
https://www.ncbi.nlm.nih.gov/pubmed/31783620
http://dx.doi.org/10.3390/pharmaceutics11120632