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In Vitro and In Vivo Assessment of Metabolic Drug Interaction Potential of Dutasteride with Ketoconazole

Dutasteride (DUT) is a selective, potent, competitive, and irreversible inhibitor of both type-1 and type-2 5α-reductase (5AR) commonly used in the treatment of benign prostatic hyperplasia and androgenetic alopecia. In the present study, we developed a simple and sensitive high-performance liquid c...

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Detalles Bibliográficos
Autores principales: Seo, Seong-Wook, Park, Jin Woo, Han, Dong-Gyun, Kim, Ji-Min, Kim, Sanghyun, Park, Taeuk, Kang, Kyung-Hwa, Yang, Min Hye, Yoon, In-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956158/
https://www.ncbi.nlm.nih.gov/pubmed/31835695
http://dx.doi.org/10.3390/pharmaceutics11120673