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In Vitro and In Vivo Assessment of Metabolic Drug Interaction Potential of Dutasteride with Ketoconazole
Dutasteride (DUT) is a selective, potent, competitive, and irreversible inhibitor of both type-1 and type-2 5α-reductase (5AR) commonly used in the treatment of benign prostatic hyperplasia and androgenetic alopecia. In the present study, we developed a simple and sensitive high-performance liquid c...
Autores principales: | Seo, Seong-Wook, Park, Jin Woo, Han, Dong-Gyun, Kim, Ji-Min, Kim, Sanghyun, Park, Taeuk, Kang, Kyung-Hwa, Yang, Min Hye, Yoon, In-Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956158/ https://www.ncbi.nlm.nih.gov/pubmed/31835695 http://dx.doi.org/10.3390/pharmaceutics11120673 |
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