A Pathway-Based Genomic Approach to Identify Medications: Application to Alcohol Use Disorder

Chronic, excessive alcohol use alters brain gene expression patterns, which could be important for initiating, maintaining, or progressing the addicted state. It has been proposed that pharmaceuticals with opposing effects on gene expression could treat alcohol use disorder (AUD). Computational stra...

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Detalles Bibliográficos
Autores principales: Ferguson, Laura B., Patil, Shruti, Moskowitz, Bailey A., Ponomarev, Igor, Harris, Robert A., Mayfield, Roy D., Messing, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956180/
https://www.ncbi.nlm.nih.gov/pubmed/31888299
http://dx.doi.org/10.3390/brainsci9120381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956180/
https://www.ncbi.nlm.nih.gov/pubmed/31888299
http://dx.doi.org/10.3390/brainsci9120381

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