Cargando…
A Pathway-Based Genomic Approach to Identify Medications: Application to Alcohol Use Disorder
Chronic, excessive alcohol use alters brain gene expression patterns, which could be important for initiating, maintaining, or progressing the addicted state. It has been proposed that pharmaceuticals with opposing effects on gene expression could treat alcohol use disorder (AUD). Computational stra...
Autores principales: | Ferguson, Laura B., Patil, Shruti, Moskowitz, Bailey A., Ponomarev, Igor, Harris, Robert A., Mayfield, Roy D., Messing, Robert O. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956180/ https://www.ncbi.nlm.nih.gov/pubmed/31888299 http://dx.doi.org/10.3390/brainsci9120381 |
Ejemplares similares
-
RNA biomarkers for alcohol use disorder
por: Ferguson, Laura B., et al.
Publicado: (2022) -
Dissecting Brain Networks Underlying Alcohol Binge Drinking Using a Systems Genomics Approach
por: Ferguson, Laura B., et al.
Publicado: (2018) -
Epigenetic modulation of brain gene networks for cocaine and alcohol abuse
por: Farris, Sean P., et al.
Publicado: (2015) -
Chronic self-administration of alcohol results in elevated ΔFosB: comparison of hybrid mice with distinct drinking patterns
por: Ozburn, Angela R, et al.
Publicado: (2012) -
Cell-type specific changes in PKC-delta neurons of the central amygdala during alcohol withdrawal
por: Dilly, Geoffrey A., et al.
Publicado: (2022)