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Doxycycline and Monocaprin In Situ Hydrogel: Effect on Stability, Mucoadhesion and Texture Analysis and In Vitro Release

The aim of this study was to develop a stable aqueous formulation containing a combination of doxycycline and monocaprin in clinically relevant concentrations. Increase in expression of Matrix metalloproteinases (MMPs) and microbial role in oral diseases is well established and the combination of ab...

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Detalles Bibliográficos
Autores principales: Patlolla, Venu Gopal Reddy, Peter Holbrook, William, Gizurarson, Sveinbjorn, Kristmundsdottir, Thordis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956273/
https://www.ncbi.nlm.nih.gov/pubmed/31835322
http://dx.doi.org/10.3390/gels5040047