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Establishing a Field-Effect Transistor Sensor for the Detection of Mutations in the Tumour Protein 53 Gene (TP53)—An Electrochemical Optimisation Approach

We present a low-cost, sensitive and specific DNA field-effect transistor sensor for the rapid detection of a common mutation to the tumour protein 53 gene (TP53). The sensor consists of a commercially available, low-cost, field-effect transistor attached in series to a gold electrode sensing pad fo...

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Detalles Bibliográficos
Autores principales: Crossley, Lisa, Attoye, Bukola, Vezza, Vincent, Blair, Ewen, Corrigan, Damion K., Hannah, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956290/
https://www.ncbi.nlm.nih.gov/pubmed/31817717
http://dx.doi.org/10.3390/bios9040141