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Homogeneous production and characterization of recombinant N-GlcNAc-protein in Pichia pastoris

BACKGROUND: Therapeutic glycoproteins have occupied an extremely important position in the market of biopharmaceuticals. N-Glycosylation of protein drugs facilitates them to maintain optimal conformations and affect their structural stabilities, serum half-lives and biological efficiencies. Thus hom...

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Detalles Bibliográficos
Autores principales: Wang, Shengjun, Rong, Yongheng, Wang, Yaoguang, Kong, Decai, Wang, Peng George, Chen, Min, Kong, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956495/
https://www.ncbi.nlm.nih.gov/pubmed/31931833
http://dx.doi.org/10.1186/s12934-020-1280-0