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Homogeneous production and characterization of recombinant N-GlcNAc-protein in Pichia pastoris
BACKGROUND: Therapeutic glycoproteins have occupied an extremely important position in the market of biopharmaceuticals. N-Glycosylation of protein drugs facilitates them to maintain optimal conformations and affect their structural stabilities, serum half-lives and biological efficiencies. Thus hom...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956495/ https://www.ncbi.nlm.nih.gov/pubmed/31931833 http://dx.doi.org/10.1186/s12934-020-1280-0 |