SELEX tool: a novel and convenient gel-based diffusion method for monitoring of aptamer-target binding

BACKGROUND: Aptamers, single-stranded DNAs or RNAs, can be selected from a library containing random sequences using a method called Systematic Evolution of Ligands by EXponential Enrichment (SELEX). In SELEX, monitoring the enriching statuses of aptamer candidates during the process is a key step u...

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Detalles Bibliográficos
Autores principales: Liu, Qingxiu, Zhang, Wei, Chen, Siying, Zhuang, Zhenjing, Zhang, Yi, Jiang, Lingli, LIN, Jun Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956507/
https://www.ncbi.nlm.nih.gov/pubmed/31956340
http://dx.doi.org/10.1186/s13036-019-0223-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956507/
https://www.ncbi.nlm.nih.gov/pubmed/31956340
http://dx.doi.org/10.1186/s13036-019-0223-y

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