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SELEX tool: a novel and convenient gel-based diffusion method for monitoring of aptamer-target binding
BACKGROUND: Aptamers, single-stranded DNAs or RNAs, can be selected from a library containing random sequences using a method called Systematic Evolution of Ligands by EXponential Enrichment (SELEX). In SELEX, monitoring the enriching statuses of aptamer candidates during the process is a key step u...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956507/ https://www.ncbi.nlm.nih.gov/pubmed/31956340 http://dx.doi.org/10.1186/s13036-019-0223-y |