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Complement C3 overexpression activates JAK2/STAT3 pathway and correlates with gastric cancer progression

BACKGROUND: Localized C3 deposition is a well-known factor of inflammation. However, its role in oncoprogression of gastric cancer (GC) remains obscured. This study aims to explore the prognostic value of C3 deposition and to elucidate the mechanism of C3-related oncoprogression for GC. METHODS: Fro...

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Detalles Bibliográficos
Autores principales: Yuan, Kaitao, Ye, Jinning, Liu, Zhenguo, Ren, Yufeng, He, Weiling, Xu, Jianbo, He, Yulong, Yuan, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956509/
https://www.ncbi.nlm.nih.gov/pubmed/31928530
http://dx.doi.org/10.1186/s13046-019-1514-3