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Membrane‐type frizzled‐related protein regulates lipidome and transcription for photoreceptor function

Molecular decision‐makers of photoreceptor (PRC) membrane organization and gene regulation are critical to understanding sight and retinal degenerations that lead to blindness. Using Mfrp(rd6)mice, which develop PRC degeneration, we uncovered that membrane‐type frizzled‐related protein (MFRP) partic...

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Detalles Bibliográficos
Autores principales: Kautzmann, Marie‐Audrey I., Gordon, William C., Jun, Bokkyoo, Do, Khanh V., Matherne, Blake J., Fang, Zhide, Bazan, Nicolas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956729/
https://www.ncbi.nlm.nih.gov/pubmed/31914617
http://dx.doi.org/10.1096/fj.201902359R