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PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness

Clinical data suggest that the protein tyrosine phosphatase PTPN13 exerts an anti-oncogenic effect. Its exact role in tumorigenesis remains, however, unclear due to its negative impact on FAS receptor-induced apoptosis. Methods: We crossed transgenic mice deleted for PTPN13 phosphatase activity with...

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Detalles Bibliográficos
Autores principales: Hamyeh, Mohamed, Bernex, Florence, Larive, Romain M., Naldi, Aurélien, Urbach, Serge, Simony-Lafontaine, Joelle, Puech, Carole, Bakhache, William, Solassol, Jérome, Coopman, Peter J., Hendriks, Wiljan J.A.J, Freiss, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956795/
https://www.ncbi.nlm.nih.gov/pubmed/31938048
http://dx.doi.org/10.7150/thno.38537