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Chimeric peptide supramolecular nanoparticles for plectin-1 targeted miRNA-9 delivery in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with poor prognosis. Insights into the roles of MicroRNAs (miRNAs) in diseases, particularly in cancer, have made miRNAs attractive tools and targets for novel therapeutic approaches. Methods: Here, we employed a novel chimeric pepti...

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Detalles Bibliográficos
Autores principales: Wu, Ying, Tang, Yuexiao, Xie, Shangzhi, Zheng, Xiaoxiao, Zhang, Shufen, Mao, Jiayan, Wang, Baoming, Hou, Yuerou, Hu, Liqiang, Chai, Kequn, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956805/
https://www.ncbi.nlm.nih.gov/pubmed/31938057
http://dx.doi.org/10.7150/thno.38327