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Smooth muscle SIRT1 reprograms endothelial cells to suppress angiogenesis after ischemia

Objective: Vascular smooth muscle cells (VSMCs) undergo the phenotypic changes from contractile to synthetic state during vascular remodeling after ischemia. SIRT1 protects against stress-induced vascular remodeling via maintaining VSMC differentiated phenotype. However, the effect of smooth muscle...

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Detalles Bibliográficos
Autores principales: Dou, Yong-Qing, Kong, Peng, Li, Chang-Lin, Sun, Hong-Xing, Li, Wei-Wei, Yu, Yuan, Nie, Lei, Zhao, Li-Li, Miao, Sui-Bing, Li, Xiao-Kun, Dong, Chen, Zhang, Jin-Wen, Liu, Yang, Huo, Xiao-Xia, Chi, Kui, Gao, Xiang, Zhang, Ning, Weng, Lin, Yang, Hongyuan, Zhang, Fan, Han, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956806/
https://www.ncbi.nlm.nih.gov/pubmed/31938060
http://dx.doi.org/10.7150/thno.39320