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Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis

Polybrominated diphenyl ethers (PBDEs)-induced neurotoxicity is closely associated with mitochondrial abnormalities. Mitochondrial fusion and fission dynamics are required for the maintenance of mitochondrial homeostasis. However, little is known about how PBDEs disrupt this dynamics and whether suc...

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Detalles Bibliográficos
Autores principales: Dong, Lixin, Li, Pei, Yang, Kaichao, Liu, Luming, Gao, Hui, Zhou, Guoyu, Zhao, Qian, Xia, Tao, Wang, Aiguo, Zhang, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956817/
https://www.ncbi.nlm.nih.gov/pubmed/31938063
http://dx.doi.org/10.7150/thno.40060