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Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression

Rationale: Glioblastoma multiforme (GBM) almost invariably gain invasive phenotype with limited therapeutic strategy and ill-defined mechanism. By studying the aberrant expression landscape of gliomas, we find significant up-regulation of p-MAPK level in GBM and a potent independent prognostic marke...

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Detalles Bibliográficos
Autores principales: Chen, Xueran, Hao, Aijun, Li, Xian, Ye, Kaiqin, Zhao, Chenggang, Yang, Haoran, Ma, Huihui, Hu, Lei, Zhao, Zhiyang, Hu, Lizhu, Ye, Fang, Sun, Qiuyan, Zhang, Huaman, Wang, Hongzhi, Yao, Xuebiao, Fang, Zhiyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956818/
https://www.ncbi.nlm.nih.gov/pubmed/31938047
http://dx.doi.org/10.7150/thno.40076