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Repression of PCGF1 Decreases the Proliferation of Glioblastoma Cells in Association with Inactivation of c-Myc Signaling Pathway

PURPOSE: Glioblastoma (GBM) is the most common primary brain tumor with a poor therapeutic outcome. Polycomb group factor 1 (PCGF1), a member of the PcG (Polycomb group) family, is highly expressed in the developing nervous system of mice. However, the function and the mechanism of PCGF1 in GBM prol...

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Detalles Bibliográficos
Autores principales: Yan, Rui, Cui, Fengmei, Dong, Lijin, Liu, Yong, Chen, Xuewei, Fan, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957096/
https://www.ncbi.nlm.nih.gov/pubmed/32021272
http://dx.doi.org/10.2147/OTT.S234517