LTA1 and dmLT enterotoxin-based proteins activate antigen-presenting cells independent of PKA and despite distinct cell entry mechanisms

Enterotoxin-based proteins are powerful manipulators of mucosal immunity. The A1 domain of heat-labile enterotoxin from E. coli, or LTA1, is a newer adjuvant from this family under investigation for intranasal vaccines. Although LTA1 has been examined in mouse vaccination studies, its ability to dir...

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Detalles Bibliográficos
Autores principales: Valli, Eduardo, Baudier, Robin L., Harriett, Amanda J., Norton, Elizabeth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957164/
https://www.ncbi.nlm.nih.gov/pubmed/31929548
http://dx.doi.org/10.1371/journal.pone.0227047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957164/
https://www.ncbi.nlm.nih.gov/pubmed/31929548
http://dx.doi.org/10.1371/journal.pone.0227047

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