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LTA1 and dmLT enterotoxin-based proteins activate antigen-presenting cells independent of PKA and despite distinct cell entry mechanisms

Enterotoxin-based proteins are powerful manipulators of mucosal immunity. The A1 domain of heat-labile enterotoxin from E. coli, or LTA1, is a newer adjuvant from this family under investigation for intranasal vaccines. Although LTA1 has been examined in mouse vaccination studies, its ability to dir...

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Detalles Bibliográficos
Autores principales:	Valli, Eduardo, Baudier, Robin L., Harriett, Amanda J., Norton, Elizabeth B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957164/ https://www.ncbi.nlm.nih.gov/pubmed/31929548 http://dx.doi.org/10.1371/journal.pone.0227047

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