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Astrovirus replication in human intestinal enteroids reveals multi-cellular tropism and an intricate host innate immune landscape

Human astroviruses (HAstV) are understudied positive-strand RNA viruses that cause gastroenteritis mostly in children and the elderly. Three clades of astroviruses, classic, MLB-type and VA-type have been reported in humans. One limitation towards a better understanding of these viruses has been the...

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Detalles Bibliográficos
Autores principales: Kolawole, Abimbola O., Mirabelli, Carmen, Hill, David R., Svoboda, Sophia A., Janowski, Andrew B., Passalacqua, Karla D., Rodriguez, Benancio N., Dame, Michael K., Freiden, Pamela, Berger, Ryan P., Vu, Diem-lan, Hosmillo, Myra, O’Riordan, Mary X. D., Schultz-Cherry, Stacey, Guix, Susana, Spence, Jason R., Wang, David, Wobus, Christiane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957189/
https://www.ncbi.nlm.nih.gov/pubmed/31671153
http://dx.doi.org/10.1371/journal.ppat.1008057