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A non-canonical role for p27(Kip1) in restricting proliferation of corneal endothelial cells during development

The cell cycle regulator p27(Kip1) is a critical factor controlling cell number in many lineages. While its anti-proliferative effects are well-established, the extent to which this is a result of its function as a cyclin-dependent kinase (CDK) inhibitor or through other known molecular interactions...

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Detalles Bibliográficos
Autores principales: Defoe, Dennis M., Rao, Huiying, Harris, David J., Moore, Preston D., Brocher, Jan, Harrison, Theresa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957298/
https://www.ncbi.nlm.nih.gov/pubmed/31929545
http://dx.doi.org/10.1371/journal.pone.0226725