Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor

Phosphoinositide 3‐kinases, delta (PI3Kδ) and gamma (PI3Kγ) are enriched in immune cells and regulate the development and function of innate and adaptive immunity. Dual PI3Kδγ inhibitors are considered high value targets for their potential to treat a variety of immune‐mediated diseases, but their d...

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Detalles Bibliográficos
Autores principales: Cai, Yu, Yu, Jun, Ren, Ping, He, Jianlin, Wu, Zhipeng, Xiao, Kun, Jia, Hong, Wang, Jian, Sai, Yang, Dai, Guangxiu, Li, Xiong, Su, Weiguo, Ngo, Karen, Castro, Glenda, Acton, Paul D., Fung‐Leung, Wai‐Ping, Edwards, James P., Venable, Jennifer, Rao, Tadimeti S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957347/
https://www.ncbi.nlm.nih.gov/pubmed/31956418
http://dx.doi.org/10.1002/prp2.559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957347/
https://www.ncbi.nlm.nih.gov/pubmed/31956418
http://dx.doi.org/10.1002/prp2.559

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