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Anosmin-1 activates vascular endothelial growth factor receptor and its related signaling pathway for olfactory bulb angiogenesis

Anosmin-1 is a secreted glycoprotein encoded by the ANOS1 gene, and its loss of function causes Kallmann syndrome (KS), which is characterized by anosmia and hypogonadism due to olfactory bulb (OB) dysfunction. However, the physiological function of anosmin-1 remains to be elucidated. In KS, disorde...

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Detalles Bibliográficos
Autores principales: Matsushima, Shoko, Shimizu, Akio, Kondo, Manami, Asano, Hirotsugu, Ueno, Nobuhiro, Nakayama, Hironao, Sato, Naoko, Komeno, Masahiro, Ogita, Hisakazu, Kurokawa-Seo, Misuzu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957483/
https://www.ncbi.nlm.nih.gov/pubmed/31932617
http://dx.doi.org/10.1038/s41598-019-57040-3