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Anosmin-1 activates vascular endothelial growth factor receptor and its related signaling pathway for olfactory bulb angiogenesis
Anosmin-1 is a secreted glycoprotein encoded by the ANOS1 gene, and its loss of function causes Kallmann syndrome (KS), which is characterized by anosmia and hypogonadism due to olfactory bulb (OB) dysfunction. However, the physiological function of anosmin-1 remains to be elucidated. In KS, disorde...
Autores principales: | Matsushima, Shoko, Shimizu, Akio, Kondo, Manami, Asano, Hirotsugu, Ueno, Nobuhiro, Nakayama, Hironao, Sato, Naoko, Komeno, Masahiro, Ogita, Hisakazu, Kurokawa-Seo, Misuzu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957483/ https://www.ncbi.nlm.nih.gov/pubmed/31932617 http://dx.doi.org/10.1038/s41598-019-57040-3 |
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