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Flexible loop and helix 2 domains of TCTP are the functional domains of dimerized TCTP

Translationally controlled tumor protein (TCTP), also called histamine releasing factor, is an evolutionarily conserved multifunctional protein in eukaryotes. We previously reported that extracellular TCTP acquires its cytokine-like function following dimerization. This study aims to identify the fu...

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Detalles Bibliográficos
Autores principales: Lee, Heewon, Kim, Mi-Sun, Lee, Ji-Sun, Cho, Hyunsoo, Park, Jimin, Hae Shin, Dong, Lee, Kyunglim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957494/
https://www.ncbi.nlm.nih.gov/pubmed/31932619
http://dx.doi.org/10.1038/s41598-019-57064-9