Direct asymmetric N-propargylation of indoles and carbazoles catalyzed by lithium SPINOL phosphate

Catalytic asymmetric functionalization of the N–H groups of indoles and carbazoles constitutes an important but less developed class of reactions. Herein, we describe a propargylation protocol involving the use of a lithium SPINOL phosphate as the chiral catalyst and our recently developed C-alkynyl...

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Detalles Bibliográficos
Autores principales: Wang, Yingcheng, Wang, Sheng, Shan, Wenyu, Shao, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957506/
https://www.ncbi.nlm.nih.gov/pubmed/31932668
http://dx.doi.org/10.1038/s41467-019-13886-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957506/
https://www.ncbi.nlm.nih.gov/pubmed/31932668
http://dx.doi.org/10.1038/s41467-019-13886-9

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