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Direct asymmetric N-propargylation of indoles and carbazoles catalyzed by lithium SPINOL phosphate
Catalytic asymmetric functionalization of the N–H groups of indoles and carbazoles constitutes an important but less developed class of reactions. Herein, we describe a propargylation protocol involving the use of a lithium SPINOL phosphate as the chiral catalyst and our recently developed C-alkynyl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957506/ https://www.ncbi.nlm.nih.gov/pubmed/31932668 http://dx.doi.org/10.1038/s41467-019-13886-9 |