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Streptococcus pneumoniae triggers hierarchical autophagy through reprogramming of LAPosome-like vesicles via NDP52-delocalization

In innate immunity, multiple autophagic processes eliminate intracellular pathogens, but it remains unclear whether noncanonical autophagy and xenophagy are coordinated, and whether they occur concomitantly or sequentially. Here, we show that Streptococcus pneumoniae, a causative of invasive pneumoc...

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Detalles Bibliográficos
Autores principales: Ogawa, Michinaga, Takada, Naoki, Shizukuishi, Sayaka, Tomokiyo, Mikado, Chang, Bin, Yoshida, Mitsutaka, Kakuta, Soichiro, Tanida, Isei, Ryo, Akihide, Guan, Jun-Lin, Takeyama, Haruko, Ohnishi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957511/
https://www.ncbi.nlm.nih.gov/pubmed/31932716
http://dx.doi.org/10.1038/s42003-020-0753-3