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Annexin-V stabilizes membrane defects by inducing lipid phase transition

Annexins are abundant cytoplasmic proteins, which bind to membranes that expose negatively charged phospholipids in a Ca(2+)-dependent manner. During cell injuries, the entry of extracellular Ca(2+) activates the annexin membrane-binding ability, subsequently initiating membrane repair processes. Ho...

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Detalles Bibliográficos
Autores principales: Lin, Yi-Chih, Chipot, Christophe, Scheuring, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957514/
https://www.ncbi.nlm.nih.gov/pubmed/31932647
http://dx.doi.org/10.1038/s41467-019-14045-w