NLRP6 self-assembles into a linear molecular platform following LPS binding and ATP stimulation

NOD-like receptors (NLRs) localize in the cytosol to recognize intracellular pathogen products and initialize the innate immune response. However, the ligands and ligand specificity of many NLRs remain unclear. One such NLR, NLRP6, plays an important role in maintaining intestinal homeostasis and pr...

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Detalles Bibliográficos
Autores principales: Leng, Fangwei, Yin, Hang, Qin, Siying, Zhang, Kai, Guan, Yukun, Fang, Run, Wang, Honglei, Li, Guohui, Jiang, Zhengfan, Sun, Fei, Wang, Da-Cheng, Xie, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957519/
https://www.ncbi.nlm.nih.gov/pubmed/31932628
http://dx.doi.org/10.1038/s41598-019-57043-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957519/
https://www.ncbi.nlm.nih.gov/pubmed/31932628
http://dx.doi.org/10.1038/s41598-019-57043-0

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