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Structural basis of homologous recombination

Homologous recombination (HR) is a pathway to faithfully repair DNA double-strand breaks (DSBs). At the core of this pathway is a DNA recombinase, which, as a nucleoprotein filament on ssDNA, pairs with homologous DNA as a template to repair the damaged site. In eukaryotes Rad51 is the recombinase c...

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Detalles Bibliográficos
Autores principales: Sun, Yueru, McCorvie, Thomas J., Yates, Luke A., Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957567/
https://www.ncbi.nlm.nih.gov/pubmed/31748913
http://dx.doi.org/10.1007/s00018-019-03365-1